Impact of embryonic Fgf10 expression deficiency on embryonic mouse lung development and repair following hyperoxia injury
نویسندگان
چکیده
s of the 51st Workshop for Pediatric Research 51st Workshop for Pediatric Research Göttingen, Germany
منابع مشابه
Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.
During lung development, parabronchial SMC (PSMC) progenitors in the distal mesenchyme secrete fibroblast growth factor 10 (Fgf10), which acts on distal epithelial progenitors to promote their proliferation. β-catenin signaling within PSMC progenitors is essential for their maintenance, proliferation, and expression of Fgf10. Here, we report that this Wnt/Fgf10 embryonic signaling cascade is re...
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